Ariane was born in Vienna, Austria (1992). Due to her early interest in cancer research, she started as a research fellow at the “Thoracic Malignacies-Research group” of the Department of Thoracic Surgery, Medical University of Vienna, in 2015 while studying medicine. This time set the foundation for her later doctoral thesis focusing on the different metastatic pattern in lung cancer. In 2018, she obtained her Medical Degree and started in the same year her PhD studies at the “CNS tumor research group” of the Division of Oncology, Medical University of Vienna under the supervision of Prof. Matthias Preusser and Prof. Anna Berghoff. In her PhD between 2018-2022, she set her research focus on the investigation of clinical and tissue-based characteristics in brain metastases from different primary tumors. Her excellent scientific work is reflected in >20 publications in this field as first- and co-author, published in international, high-ranking peer-reviewed journals. For her comprehensive research on emerging prognostic factors in brain metastases, she was awarded with the prestigious “Wolfgang-Denk-Preis” of the Austrian Society for Hematology & Medical Oncology” in 2021. For another innovative project on DNA methylation profiles of progressive brain metastases, Ariane received a grant from the “Fonds der Stadt Wien für innovative interdisziplinäre Krebsforschung”. Since 2019, Ariane is holding a resident position at the Division of Oncology, Medical University of Vienna, which she currently pauses to perform a part of her post-doc at the Valiente Lab. This internship presents for her the ultimate opportunity to improve her laboratory skills and extend her scope to basic research. Ariane’s current main project focuses on resistance pathways of progressive brain metastases after radiotherapy.