Toward plasmonic neural probes: SERS detection of neurotransmitters through gold nanoislands-decorated tapered optical fibers with sub-10 nm gaps.
Zheng D, Pisano F, Collard L, Balena A, Pisanello M, Spagnolo B, Mach-Batlle R, Tantussi F, Carbone L, De Angelis F, Valiente M, de La Prida L, Ciracì C, De Vittorio M, Pisanello F.
Advanced Materials (2022).
Protocol to generate murine organotypic brain cultures for drug screening and evaluation of anti-metastatic efficacy
Lucía Zhu, Lauritz Miarka, Patricia Baena, María Perea-García, Manuel Valiente. STAR Protocols (2023)
Our lab together with our collaborators, which include physicists, neuroscientists and engineers, are exploiting the properties of light to design, test and apply the next generation of plasmonic devices to improve the diagnosis and treatment of brain metastasis.
Low-invasive probes are designed to use the light for two purposes:
Our initial tests suggest that we have created a unique tool that could be exploited according to the two major goals.
NANOBRIGHT could establish a better scenario for diagnosing and treating brain tumors by avoiding highly invasive methodologies as well as increase the armamentarium to challenge both primary and secondary tumors in the brain.