Publications

Our publications reflect our interests in the fields of Cancer Biology and Neuroscience. This allows us to study brain metastases using a variety of techniques. Here are our most significant contributions to both disciplines.

2024. Brain Metastasis Group publications 

Next Directions in the Neuroscience of Cancers Arising outside the CNS

Cancer Discovery (2024)

First author/s: Amit M et al.
Corresponding author/s: Borniger J

Invasive growth of brain metastases is linked to CHI3L1 release from pSTAT3-positive astrocytes

Neuro-Oncology (2024)

First author/s: Dankner M, Maritan S et al.
Corresponding author/s: Siegel P

2023. Brain Metastasis Group publications 

Updating cancer research with patient-focused networks

Trends in Cancer (2023)

First author/s: Valiente M, Ortega-Paino E
Corresponding author/s: Valiente M

Growth exponents reflect evolutionary processes and treatment response in brain metastases

npj Systems Biology and Applications (2023)

First author/s: Ocaña-Tienda B et al.
Corresponding author/s: Ocaña-Tienda B

Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits

Cancer Cell (2023)

First author/s: Sanchez-Aguilera A, Masmudi-Martín M et al.
Corresponding author/s: Menéndez de la Prida L, Valiente M

Protocol to generate murine organotypic brain cultures for drug screening and evaluation of anti-metastatic efficacy

STAR Protocols (2023)

First author/s: Zhu L et al.
Corresponding author/s: Valiente M

Emerging targets for cancer treatment: S100A9/RAGE

ESMO Open (2023)

First author/s: Valiente M
Corresponding author/s: Valiente M, Sepúlveda JM, Pérez A

2022. Brain Metastasis Group publications 

Toward plasmonic neural probes: SERS detection of neurotransmitters through gold nanoislands-decorated tapered optical fibers with sub-10 nm gaps

Advanced Materials (2023)

First author/s: Zheng D et al.
Corresponding author/s: Zheng D, De Vittorio M, and Pisanello F

Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism

Nature Medicine (2022)

First author/s: Monteiro C, Miarka L et al.
Corresponding author/s: Valiente M

A clinically-compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

EMBO Molecular Medicine (2022)

First author/s: Zhu L et al.
Corresponding author/s: Valiente M

2021. Brain Metastasis Group publications 

Animal models of brain metastasis

Neuro-Oncology Advances (2021)

First author/s: Miarka L
Corresponding author/s: Valiente M

Plasmonics on a neural implant: engineering light–matter interactions on the nonplanar surface of tapered optical fibers

Advanced Optical Materials (2021)

First author/s: Pisano F et al.
Corresponding author/s: Pisano F, Pisanello F

Brain microenvironment heterogeneity: potential value for brain tumors

Frontiers in Oncology (2021)

First author/s: Álvaro-Espinosa L et al.
Corresponding author/s: Priego N

Challenges and novel opportunities of radiation therapy for brain metastases in non-small cell lung cancer

Cancers (2021)

First author/s: Jablonska PA, Bosch-Barrera J et al.
Corresponding author/s: Calvo A, Aristu J

Organotypic brain cultures for metastasis research

Neuromethods (2021)

First author/s: Zhu L
Corresponding author/s: Valiente M

Brain metastasis models: what do we need to aim for better treatments.

Adv. Drug Deliv. Rev. (2021)

First author/s: Masmudi-Martín M, Zhu L et al.
Corresponding author/s: Valiente M

2020. Brain Metastasis Group publications 

Vascular co-option in brain metastasis

Angiogenesis (2020)

First author/s: García-Gómez P
Corresponding author/s: Valiente M

Brain metastases cell partners and tumor microenvironment

Central Nervous System Metastases (2020)

First author/s: García-Gómez P et al.
Corresponding author/s: Valiente M

Universal scaling laws rule explosive growth in human cancers

Nature Physics (2020)

First author/s: Pérez-García VM et al.
Corresponding author/s: Pérez-García VM

Vascular co-option

Tumor vascularization (2020)

First author/s: García-Gómez P
Corresponding author/s: Valiente M

An inbred ecosystem that supports medulloblastoma

Immunity (2020)

First author/s: De Pablos-Aragoneses A
Corresponding author/s: Valiente M

Preclinical models of brain metastasis

Central Nervous System Metastases: Diagnosis and Treatment (2020)

First author/s: Zhu L
Corresponding author/s: Valiente M

Immunotherapy in NSCLC patients with brain metastases. Understanding brain tumor microenvironment and dissecting outcomes from immune checkpoint blockade in the clinic

Cancer Treatment Reviews (2020)

First author/s: Vilariño N et al.
Corresponding author/s: Nadal E

Brain Metastasis Cell Lines Panel: a public resource for organotropic cell lines

Cancer Research (2020)

First author/s: Valiente M et al.
Corresponding author/s: Valiente M

Breaking down the wall: the strategic plan of cancer to conquer the brain.

Epilepsy Currents (2020)

First author/s: Valiente M, de la Prida L
Corresponding author/s: Valiente M, de la Prida L

2019. Brain Metastasis Group publications 

Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis

Cell Reports (2019)

First author/s: Wingrove E et al.
Corresponding author/s: Nguyen D

The Potential of Astrocytes as Immune Modulators in Brain Tumors

Frontiers in Immunology (2019)

First author/s: Priego N
Corresponding author/s: Valiente M

2018. Brain Metastasis Group publications 

T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression

Acta Neuropathol (2018)

First author/s: Mustafa DAM et al.
Corresponding author/s: Kros JM

Recent advances in the biology and treatment of brain metastases of non-small cell lung cancer: summary of a multidisciplinary roundtable discussion

ESMO Open (2018)

First author/s: Preusser M et al.
Corresponding author/s: Preusser M

The evolving landscape of brain metastasis

Trends in Cancer (2018)

First author/s: Valiente M et al.
Corresponding author/s: Valiente M, Soffietti R

Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization

Nature Cell Biology (2018)

First author/s: Er E et al.
Corresponding author/s: Massagué J

Silibinin is a direct inhibitor of STAT3

Food Chem Toxicol (2018)

First author/s: Verdura S et al.
Corresponding author/s: Bosch-Barrera J

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis

Nature Medicine (2018)

First author/s: Priego N et al.
Corresponding author/s: Valiente M

2017. Brain Metastasis Group publications 

Neuregulin 3 Mediates Cortical Plate Invasion and Laminar Allocation of GABAergic Interneurons

Cell Reports (2017)

First author/s: Bartolini G et al.
Corresponding author/s: Marín O

Reactive Astrocytes in Brain Metastasis

Frontiers in Oncology (2017)

First author/s: Wasilewsky D et al.
Corresponding author/s: Valiente M

2014-2009. Brain Metastasis Group publications 

Migration of cortical interneurons relies on branched leading processes dynamics

Cell Adhesion & Migration (2009)

First author/s: Valiente M, Martini FJ
Corresponding author/s: Valiente M, Martini FJ

Biased selection of leading process branches mediates chemotaxis during tangential neuronal migration

Development (2009)

First author/s: Martini FJ, Valiente M et al.
Corresponding author/s: Valdeolmillos M, Marín O

Control of cortical GABA circuitry development by Nrg1 and ErbB4

Nature (2010)

First author/s: Fazzari P et al.
Corresponding author/s: Marín O

Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons

J. Comp. Neurol. (2010)

First author/s: Martín-Ibáñez R et al.
Corresponding author/s: Canals JM

Guiding Neuronal Cell Migrations

Cold Spring Harb. Perspect. Biol. (2010)

First author/s: Marín O et al.
Corresponding author/s: Marín O

Neuronal migration mechanisms in development and disease

Curr. Opin. Neurobiol. (2010)

First author/s: Valiente M
Corresponding author/s: Marín O

Focal Adhesion Kinase modulates radial glia-dependent neuronal migration through Connexin-26

J Neurosci (2011)

First author/s: Valiente M et al.
Corresponding author/s: Marín O

Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis

Cell (2014)

First author/s: Valiente M et al.
Corresponding author/s: Massagué J

Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer

eLife (2014)

First author/s: Vanharanta S et al.
Corresponding author/s: Massagué J

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