We have considerable experience in the fields of Cancer Biology and Neuroscience what make us a unique laboratory for studying secondary tumors that affect the brain.
The laboratory started its operation in March 2015 to develop research in brain metastasis. Brain metastasis is a common and deadly cancer progression. When metastatic cells reach the brain after leaving the primary tumor (located, for example, in the breast or lung), the prognosis is always bad.
Systemic therapies are more effective in controlling other forms of metastasis rather when these affect the brain, therefore, the incidence of brain metastasis is on the rise. In fact brain metastases are currently the most common neurological complication of cancer, even more frequent than all brain primary tumors (such as glioblastoma) combined. The specific characteristics of the brain require new approaches to study metastatic disease in this organ.
In the laboratory we try to understand how cells from different cancer types (breast or lung among others) are able to get access to the brain, survive and colonize this vital organ. We do it by using innovative approaches resulting from combining Cancer Biology and Neuroscience.
Our goal is to understand the biology of brain metastases using experimental mouse models to develop new opportunities in the treatment of patients suffering from this disease.